Document Detail


Host defenses against zygomycetes.
MedLine Citation:
PMID:  22247447     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Mucormycosis is a devastating disease and can occur in patients with a variety of risk factors, the most important of which are immunosuppression, anatomic barrier breakdown, iron overload, and hyperglycemia/acidosis. Similarly to what occurs with Aspergillus, the host stimulates an innate immune response against the challenging sporangiospores and invading hyphae of Zygomycetes. This article discusses the host defense to different Zygomycetes, its augmentation, and its subsequent impact on the outcome of mucormycosis.
Authors:
Emmanuel Roilides; Dimitrios P Kontoyiannis; Thomas J Walsh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  54 Suppl 1     ISSN:  1537-6591     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S61-6     Citation Subset:  IM    
Affiliation:
Third Department of Pediatrics, Aristotle University, Hippokration Hospital, Thessaloniki, Greece.
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