| Host and graft thickness after Descemet stripping endothelial keratoplasty for Fuchs endothelial dystrophy. | |
| | |
MedLine Citation:
|
PMID: 20688317 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine relationships between vision, forward scatter, and total corneal and graft thicknesses after Descemet stripping endothelial keratoplasty (DSEK). DESIGN: Prospective, cohort study. METHODS: Forty-four eyes with Fuchs endothelial dystrophy were examined before and at 1, 3, 6, and 12 months after DSEK; all eyes were pseudophakic after surgery. Central total corneal and graft thicknesses were measured using confocal microscopy. Best-corrected high-contrast visual acuity (BCVA) was measured using the electronic Early Treatment Diabetic Retinopathy Study protocol, and forward light scatter was measured using a straylight meter. RESULTS: Total corneal thickness was 610 ± 50 μm (mean ± standard deviation) before DSEK, increased to 680 ± 74 μm by 1 month after DSEK (P < .001), and stabilized at 660 ± 68 μm by 3 months after DSEK (P = .03 vs 1 month). Graft thickness was 170 ± 57 μm at 1 month, decreased to 157 ± 49 μm by 3 months (P = .004), and then remained stable through 12 months (156 ± 51 μm; P = .99 vs 3 months). BCVA was 0.44 ± 0.21 logarithm of the minimal angle of resolution (logMAR) units (Snellen equivalent, 20/55) before DSEK, improved to 0.26 ± 0.20 logMAR units (Snellen equivalent, 20/36) by 3 months (P < .001), and improved to 0.16 ± 0.16 logMAR units (Snellen equivalent, 20/29) at 12 months (P < .001 vs 3 months). BCVA and forward light scatter did not correlate with corneal or graft thickness after DSEK. CONCLUSIONS: Stromal edema resolves by 3 months after DSEK for Fuchs dystrophy, whereas visual acuity continues to improve through 12 months. Thicker corneas and grafts are not associated with worse visual acuity or increased forward scatter. |
| | |
Authors:
|
Kamran A Ahmed; Jay W McLaren; Keith H Baratz; Leo J Maguire; Katrina M Kittleson; Sanjay V Patel |
Related Documents
:
|
14700097 - The effect of anterior chamber maintainer on anterior chamber contamination. 23306297 - Dabigatran vs. low molecular weight heparin in preventing venous thromboembolism after ... 18820657 - Case-control study of subconjunctival triamcinolone acetonide injection vs intravenous ... 16783147 - The effect of combinations of flurbiprofen, low molecular weight heparin, and doxycycli... 18724167 - Intravenous immunoglobulin therapy for refractory ocular cicatricial pemphigoid: case r... 21345487 - Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium,... |
Publication Detail:
|
Type: Journal Article Date: 2010-08-04 |
Journal Detail:
|
Title: American journal of ophthalmology Volume: 150 ISSN: 1879-1891 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-24 Completed Date: 2010-10-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
|
Languages: eng Pagination: 490-497.e2 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Anthropometry Body Weights and Measures Cohort Studies Cornea / pathology Descemet Stripping Endothelial Keratoplasty* Endothelium, Corneal / pathology*, transplantation Follow-Up Studies Fuchs' Endothelial Dystrophy / surgery* Humans Microscopy, Confocal Middle Aged Organ Transplantation Prospective Studies Visual Acuity / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ischemic diabetic retinopathy may protect against nuclear sclerotic cataract.
Next Document: Evaluation of the multivariate accommodation performance of the grid method.