Document Detail


Hospitalized late preterm mild preeclamptic patients with mature lung testing: what are the risks of delivery?
MedLine Citation:
PMID:  19158802     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the risk of elective delivery of hospitalized patients with isolated mild preeclampsia with mature fetal lung profile compared with a cohort of patients who had preeclampsia with indicated delivery matched for gestational age.
STUDY DESIGN: Patients with mild preeclampsia requiring hospitalization between 34 and 37 weeks estimated gestational age were offered amniocentesis for assessment of fetal lung maturity. If fetal lung maturity was documented, patients were offered delivery. These cases were then compared with indicated or spontaneously delivered controls with preeclampsia matched for gestational age.
RESULT: A total of 51 cases were identified and matched with 51 controls. Sixteen case neonates (31.4%) were admitted to neonatal intensive care unit compared with 21 controls (41.2%). Five cases (9.8%) in each group developed respiratory distress syndrome (RDS).
CONCLUSION: Elective delivery of mild preeclampsia with mature lung profiles in the late preterm gestation is not without neonatal risks, including a 10% risk of RDS in this series.
Authors:
D F Lewis; J McCann; Y Wang; C Cormier; L Groome
Publication Detail:
Type:  Journal Article     Date:  2009-01-22
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  29     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-28     Completed Date:  2009-08-17     Revised Date:  2011-07-26    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  413-5     Citation Subset:  IM    
Affiliation:
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, LA, USA. david.lewis@uc.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fetal Organ Maturity
Gestational Age*
Humans
Infant, Newborn
Infant, Premature
Intensive Care Units, Neonatal
Lung / embryology*
Pre-Eclampsia*
Pregnancy
Respiratory Distress Syndrome, Newborn / etiology*
Retrospective Studies
Risk Factors
Young Adult
Grant Support
ID/Acronym/Agency:
R01 HD036822-08/HD/NICHD NIH HHS; R01 HL065997-08/HL/NHLBI NIH HHS
Comments/Corrections

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