Document Detail

Hospital-wide prospective mandatory surveillance of invasive aspergillosis in a French teaching hospital (2000-2002).
MedLine Citation:
PMID:  16257084     Owner:  NLM     Status:  MEDLINE    
A multidisciplinary working group devoted to epidemiological surveillance of invasive aspergillosis (IA) was created in January 2000 in Grenoble University Hospital. This article presents the results of a three-year IA surveillance. The multidisciplinary working group surveyed all hospitalized patients, and the mycology laboratory detected most suspected IA cases. Cases were reviewed monthly by the Aspergillosis Committee, and were classified according to international consensus criteria. Possible nosocomial acquisition was determined. Among the 490 alerts, 74 IA cases were observed: six proven cases (8%), 36 (49%) probable cases and 32 (43%) possible cases. The incidence was 4.4 (95% CI 3.4-5.4) IA/100 000 patient-days. Among the proven and probable IA cases, we observed 10 nosocomial cases and six cases of undetermined origin. No cases were noted in the protected rooms in the haematology unit. Only one cluster of cases (three nosocomial cases) was detected in the haematology unit. Forty-three percent of cases (N=32) were hospitalized in the haematology unit, and all other cases were hospitalized elsewhere. This three-year survey found a high rate of non-nosocomial IA cases and a high frequency of IA cases hospitalized in units other than haematology. Thus, this study shows the importance of IA surveillance in haematology units and all high-risk units.
A Fourneret-Vivier; B Lebeau; M R Mallaret; M P Brenier-Pinchart; J P Brion; C Pinel; F Garban; C Pison; R Hamidfar; D Plantaz; H Pelloux; R Grillot
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Publication Detail:
Type:  Journal Article     Date:  2005-10-27
Journal Detail:
Title:  The Journal of hospital infection     Volume:  62     ISSN:  0195-6701     ISO Abbreviation:  J. Hosp. Infect.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-27     Completed Date:  2006-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007166     Medline TA:  J Hosp Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  22-8     Citation Subset:  IM    
Infection Control Unit, Grenoble University Hospital, Grenoble Cedex 9, France.
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MeSH Terms
Aspergillosis / epidemiology*,  microbiology
Aspergillus / classification,  isolation & purification*
Cross Infection / epidemiology*,  microbiology
France / epidemiology
Hematologic Diseases
Hospital Units
Hospitals, Teaching*
Middle Aged
Population Surveillance / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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