| Hospital-based use of therapeutic hypothermia after cardiac arrest in adults. | |
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MedLine Citation:
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PMID: 19231920 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Improving survival and brain function after initial resuscitation from cardiac arrest remains a critical challenge with few therapeutic options. The publication of several randomized controlled trials supporting the use of therapeutic hypothermia in cardiac arrest survivors has provided a remarkable opportunity to reduce mortality and neurologic disability from this leading cause of death. On the strength of these trials, therapeutic hypothermia has now been incorporated in the American Heart Association guidelines for post-resuscitation care. This review will focus on the hospital-based application of therapeutic hypothermia in adult cardiac arrest survivors, with special attention to practical aspects of cooling, protocol development, and evaluation of recent data from "real world" experiences using hypothermia as a treatment option. Finally, remaining research questions and directions for future improvements in therapy will be discussed. |
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Authors:
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Noah T Sugerman; Benjamin S Abella |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of neurotrauma Volume: 26 ISSN: 1557-9042 ISO Abbreviation: J. Neurotrauma Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-03-18 Completed Date: 2009-07-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8811626 Medline TA: J Neurotrauma Country: United States |
Other Details:
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Languages: eng Pagination: 371-6 Citation Subset: IM |
Affiliation:
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Department of Emergency Medicine and Center for Resuscitation Science, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Body Temperature
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physiology Brain / blood supply, metabolism, physiopathology Clinical Protocols / standards Guidelines as Topic Heart Arrest / complications* Hospitals / statistics & numerical data*, trends Humans Hypothermia, Induced / methods*, statistics & numerical data, trends Hypoxia-Ischemia, Brain / etiology*, physiopathology, therapy* Outcome Assessment (Health Care) / methods Resuscitation / methods*, statistics & numerical data, trends |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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