| Hospital-based medication reconciliation practices: a systematic review. | |
| | |
MedLine Citation:
|
PMID: 22733210 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Medication discrepancies at care transitions are common and lead to patient harm. Medication reconciliation is a strategy to reduce this risk. OBJECTIVES: To summarize available evidence on medication reconciliation interventions in the hospital setting and to identify the most effective practices. DATA SOURCES: MEDLINE (1966 through February 2012) and a manual search of article bibliographies. STUDY SELECTION: Twenty-six controlled studies. DATA EXTRACTION: Data were extracted on study design, setting, participants, inclusion/exclusion criteria, intervention components, timing, comparison group, outcome measures, and results. DATA SYNTHESIS: Studies were grouped by type of medication reconciliation intervention-pharmacist related, information technology (IT), or other-and were assigned quality ratings using US Preventive Services Task Force criteria. RESULTS: Fifteen of 26 studies reported pharmacist-related interventions, 6 evaluated IT interventions, and 5 studied other interventions. Six studies were classified as good quality. The comparison group for all the studies was usual care; no studies compared different types of interventions. Studies consistently demonstrated a reduction in medication discrepancies (17 of 17 studies), potential adverse drug events (5 of 6 studies), and adverse drug events (2 of 2 studies) but showed an inconsistent reduction in postdischarge health care utilization (improvement in 2 of 8 studies). Key aspects of successful interventions included intensive pharmacy staff involvement and targeting the intervention to a high-risk patient population. CONCLUSIONS: Rigorously designed studies comparing different inpatient medication reconciliation practices and their effects on clinical outcomes are scarce. Available evidence supports medication reconciliation interventions that heavily use pharmacy staff and focus on patients at high risk for adverse events. Higher-quality studies are needed to determine the most effective approaches to inpatient medication reconciliation. |
| | |
Authors:
|
Stephanie K Mueller; Kelly Cunningham Sponsler; Sunil Kripalani; Jeffrey L Schnipper |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
|
Title: Archives of internal medicine Volume: 172 ISSN: 1538-3679 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2012 Jul |
Date Detail:
|
Created Date: 2012-07-24 Completed Date: 2012-10-11 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1057-69 Citation Subset: AIM; IM |
Affiliation:
|
Brigham and Women's Hospital Hospitalist Service and Division of General Medicine, Brigham and Women's Hospital, Boston, MA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Drug Toxicity
/
prevention & control Humans Medication Reconciliation* |
| Grant Support | |
ID/Acronym/Agency:
|
1 R18 HS019598-01/HS/AHRQ HHS; R01 HL089755/HL/NHLBI NIH HHS; R01 HL089755/HL/NHLBI NIH HHS; T32-HP10251//PHS HHS |
| Comments/Corrections | |
Comment In:
|
Arch Intern Med. 2012 Jul 23;172(14):1069-70
[PMID:
22733283
]
JAMA Intern Med. 2013 Feb 11;173(3):246-7 [PMID: 23400661 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A simplified protocol for genetic transformation of switchgrass (Panicum virgatum L.).
Next Document: Insights into cell membrane microdomain organization from live cell single particle tracking of the ...