Document Detail

Horseshoe kidney: a new theory on its embryogenesis based on the study of a 16-mm human embryo.
MedLine Citation:
PMID:  3228209     Owner:  NLM     Status:  MEDLINE    
We studied a human embryo of 16 mm crown-rump (CR) length in excellent condition with a horseshoe kidney malformation. An exhaustive study of this specimen and a review of published material on the human embryo brings us to propose a new theory on the embryogenesis of this malformation. The most commonly accepted theory consists of a mechanical interpretation based on the relation between the metanephroi and the umbilical arteries during the development of the latter. Nevertheless, in those cases where renal parenchyma constitutes the isthmic region, we believe that these arise from nephrogenic cells that have migrated across the primitive streak in the final phase of gastrulation and thus arise from the posterior nephrogenic area of the epiblast.
J M Doménech-Mateu; X Gonzalez-Compta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Anatomical record     Volume:  222     ISSN:  0003-276X     ISO Abbreviation:  Anat. Rec.     Publication Date:  1988 Dec 
Date Detail:
Created Date:  1989-03-29     Completed Date:  1989-03-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370540     Medline TA:  Anat Rec     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  408-17     Citation Subset:  IM    
Faculty of Medicine, Department of Anatomy, Autonomous University of Barcelona, Spain.
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MeSH Terms
Embryonic and Fetal Development*
Kidney / abnormalities*,  embryology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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