Document Detail


Hormones in the naso-oropharynx: endocrine modulation of taste and smell.
MedLine Citation:
PMID:  19359194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Olfaction and gustation are important sensory modalities for locating food and for determining which foodstuffs to ingest. It is becoming apparent that there is a strong link between olfaction, gustation and metabolic control. Because endocrine signaling in the naso-oropharynx is likely to influence food intake, satiety and general metabolic control, it is important to examine some of the major hormones that play an integral part in energy homeostasis. Here, we provide an overview of the main endocrine factors known to be present in the naso-oropharynx and discuss their functional roles in maintaining metabolic function. Gaining a greater appreciation of how flavor perception is linked to peripheral metabolism could lead to novel therapeutic strategies for obesity and lifestyle-related diseases.
Authors:
Bronwen Martin; Stuart Maudsley; Caitlin M White; Josephine M Egan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural; Review     Date:  2009-04-07
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  20     ISSN:  1879-3061     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-01     Completed Date:  2009-09-24     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  163-70     Citation Subset:  IM    
Affiliation:
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD 21224, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Hormones / metabolism,  physiology*
Humans
Models, Biological
Nasopharynx / metabolism*
Oropharynx / metabolism*
Smell / physiology*
Taste / physiology*
Grant Support
ID/Acronym/Agency:
Z01 AG000291-01/AG/NIA NIH HHS; Z01 AG000318-01/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Hormones
Comments/Corrections

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