Document Detail

Hormones: beneficial or dangerous to the aged?
MedLine Citation:
PMID:  632497     Owner:  NLM     Status:  MEDLINE    
Postmenopausal women lose 75-85 percent of estrogen and progesterone production compared with that in their reproductive years. The marked decrease in estrogen results in changes in the uterus, cervix, vaginal lining, glandular breast tissue, and the rate at which bone loses thickness. Some of these changes result in symptoms which range from unpleasant to disabling. Many of the symptoms can be alleviated by treatment with estrogens. However, recent reports have been linking estrogen usage with carcinoma of the uterus. Postmenopausal women should be treated with estrogens when the situation demands, but the dosage should be kept as low as possible and progestational agents should also be administered.
C Longcope
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Geriatrics Society     Volume:  26     ISSN:  0002-8614     ISO Abbreviation:  J Am Geriatr Soc     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-05-24     Completed Date:  1978-05-24     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  7503062     Medline TA:  J Am Geriatr Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  145-8     Citation Subset:  IM    
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MeSH Terms
Breast Neoplasms / chemically induced
Estrogens / adverse effects,  therapeutic use*
Osteoporosis / prevention & control
Progesterone / adverse effects,  therapeutic use*
Uterine Neoplasms / chemically induced
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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