Document Detail

Hormone therapy and the cardiovascular system.
MedLine Citation:
PMID:  12361883     Owner:  NLM     Status:  MEDLINE    
The cardiovascular effects of female sex steroids have many faces and are very complex. To make this situation even more complicated different disease situations, different target organs and different therapeutic regimens may exhibit different effects of estrogens and progestines. Furthermore, the interpretation of population studies may be problematic by itself, in view of so many confounders and biases involved and methodological flaws that sometimes are discovered only post-hoc. It seems, therefore, that in such a complicated situation making definite conclusions and guidelines is almost an impossible task. My suggestion to clinicians is to try and follow the main stream of clinical data, looking at the general picture rather than the small details, and try to individualize therapy in order to maximize the benefits and minimize the adverse reactions and risks. This article discusses the current knowledge on hormone replacement therapy (HRT) and the cardiovascular system. It is not an overview, because my intention was not to pump in as much data as possible. Rather, the article presents current ideas and trends in this field to be used by people who practice menopause medicine for their own clinical decisions.
Amos Pines
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Maturitas     Volume:  43 Suppl 1     ISSN:  0378-5122     ISO Abbreviation:  Maturitas     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-10-03     Completed Date:  2002-11-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7807333     Medline TA:  Maturitas     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  S3-10     Citation Subset:  IM    
Department of Medicine T, Ichilov Hospital, 6 Weizman Street, Tel-Aviv 64239, Israel.
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MeSH Terms
Cardiovascular Diseases / prevention & control*
Estrogen Replacement Therapy*
Physician's Practice Patterns / trends
Women's Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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