Document Detail


Hormonal regulation of female proceptivity and its influence on male sexual preference in rats.
MedLine Citation:
PMID:  6364188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two experiments were conducted that assessed the effect of varying levels of female proceptive/attractive behaviors on male sexual preferences in sexually experienced rats. In Experiment 1, adult ovariectomized Sprague-Dawley rats were brought into behavioral estrus by a combination of estradiol-17 beta-benzoate (EB) (4 micrograms) and progesterone (500 micrograms). In addition, females received an injection of either the anti-estrogen CI-628 (1 mg) or the control vehicle (10% ethanol) only. In tests for sexual responsiveness, CI-628 caused a 3 to 4 fold decline in proceptive behavior along with a small but significant decline in receptivity. When individual males were placed in a testing arena with a pair of receptive females, only one of which received CI-628, males displayed a preference for the control-group females, as measured by overall copulatory rate. However, males did not display a consistent preference towards females of either treatment, as measured by choice of female for ejaculation. Similarly, there were no significant correlations between female proceptive behaviors and either overall copulatory rate or ejaculation. In Experiment 2, females came into behavioral estrus after being given four daily injections of EB followed by either a single injection of progesterone or just the oil vehicle. The absence of progesterone caused a significant decline in receptivity and almost entirely eliminated proceptive behaviors. When males were tested with a pair of females, only one of which received progesterone, males preferred the progesterone-injected female as measured by overall copulatory rate. However, similar to Experiment 1, no consistent preferences were evident when measured by using choice of female for ejaculation.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
I T Landau; J E Madden
Related Documents :
3835728 - Effects of an anabolic steroid on reproduction in female rats.
17948238 - Sexual dimorphism and androgen regulation of satellite cell population in differentiati...
24254498 - Modification of tissue distribution of trace elements by cyclosporin in rats.
20660998 - Improvement of hyperglycemia and sexual dysfunction in diabetic female rats by an artif...
8896818 - Chronic morphine decreases calbindin d28k immunoreactivity in a subset of cerebellar pu...
21790908 - Improved cognitive flexibility in serotonin transporter knockout rats is unchanged foll...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physiology & behavior     Volume:  31     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-03-12     Completed Date:  1984-03-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  679-85     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Castration
Copulation
Estradiol / pharmacology*
Female
Male
Muridae
Nitromifene / pharmacology
Progesterone / pharmacology*
Rats
Rats, Inbred Strains
Sexual Behavior, Animal / drug effects*
Chemical
Reg. No./Substance:
10448-84-7/Nitromifene; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Perspectives on functional adaptation of the high altitude native.
Next Document:  Short photoperiods reduce winter energy requirements of the meadow vole, Microtus pennsylvanicus.