Document Detail


Hormonal regulation during a 60-day confinement (ESA-EXEMSI'92) in humans.
MedLine Citation:
PMID:  11538919     Owner:  NASA     Status:  MEDLINE    
Abstract/OtherAbstract:
EXEMSI'92 was a 60-day isolation and confinement experiment with an international crew. During this second experiment of the European Space Agency (the first one was a 28-day confinement with 6 men: ISEMSI'90), blood volume regulating hormones and water balance were studied. During ISEMSI'90, stress level was elevated as shown by specific markers and we observed some interesting results which have been already observed before, during bed-rest experiments. Thus, our conclusion was that some of the physiological effects observed during bed rest could be the consequence of the "confinement effect" and/or stress imposed to the subjects during such experiments. The aim of the present physiological study was: 1/to define the origin of the blood pressure increase seen during ISEMSI'90; 2/ to study the blood volume regulating hormones (ANP, renin, aldosterone) variations; 3/ to determine the dehydration level by measuring the total body water with the doubly labeled water (DLW) method and fluid balance in general.
Authors:
A Maillet; H C Gunga; S Normand; A M Allevard; C Pachiaudi; F Strollo; K A Kirsch; G Gauquelin-Koch; C Gharib
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology     Volume:  2     ISSN:  1077-9248     ISO Abbreviation:  J Gravit Physiol     Publication Date:  1995  
Date Detail:
Created Date:  1996-10-18     Completed Date:  1996-10-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9437868     Medline TA:  J Gravit Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  P25-6     Citation Subset:  S    
Affiliation:
Lab. Physio. de l'Environnement Lyon, France.
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MeSH Terms
Descriptor/Qualifier:
Aldosterone / blood
Atrial Natriuretic Factor / blood*
Blood Pressure / physiology*
Body Water / metabolism
Body Weight
Catecholamines / blood,  urine
Female
Humans
Hydrocortisone / blood
Male
Renin / blood
Renin-Angiotensin System / physiology*
Social Isolation*
Space Flight
Water-Electrolyte Balance / physiology*
Chemical
Reg. No./Substance:
0/Catecholamines; 50-23-7/Hydrocortisone; 52-39-1/Aldosterone; 85637-73-6/Atrial Natriuretic Factor; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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