| Hormonal monitoring of early pregnancy by a direct radioimmunoassay of steroid glucuronides in first morning urine. | |
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MedLine Citation:
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PMID: 6489546 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The usefulness of the direct 4-hour radioimmunoassay of estriol-16-glucuronide (E3G) and pregnanediol-3-glucuronide (P2G) in first morning urine (FMU) for establishing a prognosis of the early pregnancy outcome was evaluated in 106 patients that became pregnant. Microaliquots of FMU were serially assayed from day 3 of the conception cycle until day 80 of pregnancy. The E3G and P2G profiles of 19 pregnancies which terminated in spontaneous abortion with either a diagnosis of the blighted ovum syndrome (n = 11) or presumption of a corpus luteum/trophoblast failure (n = 8) have been compared with those of clinically normal pregnancies (n = 87). Normal pregnancies displayed typical patterns of E3G and P2G development, while variations were observed in abortive events that reflected changes of the fetoplacental unit. |
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Authors:
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A F Mendizábal; S Quiroga; Z Farinati; M Lahoz; C Nagle |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 42 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1984 Nov |
Date Detail:
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Created Date: 1984-12-18 Completed Date: 1984-12-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 737-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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diagnosis Estriol / analogs & derivatives*, urine Female Humans Pregnancy* Pregnanediol / analogs & derivatives*, urine Prognosis Radioimmunoassay |
| Chemical | |
Reg. No./Substance:
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1852-49-9/pregnanediol-3 alpha-glucuronide; 26445-07-8/Pregnanediol; 28808-07-3/estriol glucuronide; 50-27-1/Estriol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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