| Hormonal control of spermatogenesis. | |
| | |
MedLine Citation:
|
PMID: 18406689 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
FSH and testosterone (T) secretion are essential for the successful completion of spermatogenesis. Because there are no receptors for FSH or testosterone on germ cells, there are intermediate steps in this action, the nature of which are unknown. However, as the Sertoli cell contains receptors for both FSH and T, it is likely that these hormones exert their influence on germ cells by modulating Sertoli cell function. Both FSH and T exert synergistic actions on germ cells, but T has a specific action on the later stages of spermatid maturation. FSH, by its ability to stimulate Sertoli cell mitosis during testicular development, can influence the spermatogenic capacity of the adult testis. |
| | |
Authors:
|
R I McLachlan; N G Wreford; D M Robertson; D M de Kretser |
Related Documents
:
|
6100019 - Identification and possible function of pro-opiomelanocortin-derived peptides in the te... 8070619 - Differential distribution of the alpha 6 subunit of integrins in the development and se... 6083809 - Serological and biochemical identification of a plasma membrane antigen specific to ley... 2212929 - Effects of hypophysectomy and human chorionic gonadotrophin on leydig cell function in ... 3963419 - A new approach to quantification of sertoli cells that avoids problems associated with ... 1917689 - Mitosis in normal adult guinea pig leydig cells. 21665149 - Cell of origin of small cell lung cancer: inactivation of trp53 and rb1 in distinct cel... 3321379 - Proliferative activity of cells in the synovium as demonstrated by a monoclonal antibod... 8790939 - Differentiation of beating cardiac muscle cells from a derivative of p19 embryonal carc... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Trends in endocrinology and metabolism: TEM Volume: 6 ISSN: 1043-2760 ISO Abbreviation: Trends Endocrinol. Metab. Publication Date: 1995 Apr |
Date Detail:
|
Created Date: 2008-04-14 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9001516 Medline TA: Trends Endocrinol Metab Country: United States |
Other Details:
|
Languages: eng Pagination: 95-101 Citation Subset: - |
Affiliation:
|
Prince Henry's Institute of Medical Research Clayton, Victoria, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Glucocorticoid resistance in humans.
Next Document: Inactivation of thyrotropin-releasing hormone (TRH) by the hormonally regulated TRH-degrading ectoen...