| Horizontal chromosome transfer, a mechanism for the evolution and differentiation of a plant-pathogenic fungus. | |
| | |
MedLine Citation:
|
PMID: 19749175 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The tomato pathotype of Alternaria alternata produces host-specific AAL toxin and causes Alternaria stem canker on tomato. A polyketide synthetase (PKS) gene, ALT1, which is involved in AAL toxin biosynthesis, resides on a 1.0-Mb conditionally dispensable chromosome (CDC) found only in the pathogenic and AAL toxin-producing strains. Genomic sequences of ALT1 and another PKS gene, both of which reside on the CDC in the tomato pathotype strains, were compared to those of tomato pathotype strains collected worldwide. This revealed that the sequences of both CDC genes were identical among five A. alternata tomato pathotype strains having different geographical origins. On the other hand, the sequences of other genes located on chromosomes other than the CDC are not identical in each strain, indicating that the origin of the CDC might be different from that of other chromosomes in the tomato pathotype. Telomere fingerprinting and restriction fragment length polymorphism analyses of the A. alternata strains also indicated that the CDCs in the tomato pathotype strains were identical, although the genetic backgrounds of the strains differed. A hybrid strain between two different pathotypes was shown to harbor the CDCs derived from both parental strains with an expanded range of pathogenicity, indicating that CDCs can be transmitted from one strain to another and stably maintained in the new genome. We propose a hypothesis whereby the ability to produce AAL toxin and to infect a plant could potentially be distributed among A. alternata strains by horizontal transfer of an entire pathogenicity chromosome. This could provide a possible mechanism by which new pathogens arise in nature. |
| | |
Authors:
|
Yasunori Akagi; Hajime Akamatsu; Hiroshi Otani; Motoichiro Kodama |
Related Documents
:
|
2671935 - Completion of the detailed restriction map of the e. coli genome by the isolation of ov... 2888835 - Genetic analysis of variant pilin genes from neisseria gonorrhoeae p9 cloned in escheri... 22352455 - Enhanced electricity production by use of reconstituted artificial consortia of estuari... 8423455 - Genome analysis of adenovirus 4 isolated over a six year period. 9594935 - Fungicidal versus fungistatic activity of terbinafine and itraconazole: an in vitro com... 22736825 - Aphelenchoides hylurgi as a carrier of white, hypovirulent cryphonectria parasitica and... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-11 |
Journal Detail:
|
Title: Eukaryotic cell Volume: 8 ISSN: 1535-9786 ISO Abbreviation: Eukaryotic Cell Publication Date: 2009 Nov |
Date Detail:
|
Created Date: 2009-11-02 Completed Date: 2010-01-14 Revised Date: 2010-09-27 |
Medline Journal Info:
|
Nlm Unique ID: 101130731 Medline TA: Eukaryot Cell Country: United States |
Other Details:
|
Languages: eng Pagination: 1732-8 Citation Subset: IM |
Affiliation:
|
Laboratory of Plant Pathology, Faculty of Agriculture, Tottori University, 4-101 Koyama-Minami, Tottori 680-8553, Japan. |
| Data Bank Information | |
Bank Name/Acc. No.:
|
GENBANK/AB465630; AB465631; AB465632; AB465633; AB465634; AB465635; AB465636; AB465637; AB465638; AB465639; AB465640; AB465641; AB465642; AB465643; AB465644; AB465645; AB465646; AB465647; AB465648; AB465649; AB465650; AB465651; AB465652; AB465653; AB465654; AB465655; AB465656; AB465657; AB465658; AB465659; AB465660; AB465661; AB465662; AB465663; AB465664; AB465665; AB465666; AB465667; AB465668; AB465669; AB465670; AB465671; AB465672; AB465673; AB465674; AB465675; AB465676; AB465677; AB465678; AB465679; AB465680; AB465681; AB465682; AB465683; AB465684; AB465685; AB465686; AB465687; AB468132; AB468133; AB468134; AB468135; AB468136; AB468137; AB468138; AB468139; AB468140; AB468141; AB468142; AB468143; AB468144; AB468145; AB468146; AB468147; AB468148; AB468149; AB468150; AB468151 |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alternaria
/
classification,
enzymology,
genetics*,
pathogenicity Chromosomes, Fungal / genetics* Evolution, Molecular* Fungal Proteins / genetics, metabolism Gene Transfer, Horizontal* Lycopersicon esculentum / microbiology* Molecular Sequence Data Phylogeny Plant Diseases / microbiology* Polyketide Synthases / genetics, metabolism Sphingosine / metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Alternaria alternata pathotoxin TA; 0/Fungal Proteins; 123-78-4/Sphingosine; 79956-01-7/Polyketide Synthases |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A contiguous compartment functions as endoplasmic reticulum and endosome/lysosome in Giardia lamblia...
Next Document: Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae gr...