| Hopes, disillusions and more hopes from vitamin C. | |
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MedLine Citation:
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PMID: 14745499 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the current view of most biochemists and physiologists, the role of L-ascorbic acid (AA) in cell metabolism would be more or less confined to the scavenging of reactive oxygen species. Nevertheless, many data have been collected in our and other laboratories concerning the involvement of AA in many different aspects of cell metabolism. At the present time the molecular sites of action of AA have not been completely elucidated, but recent findings on the specific requirement of AA for the activity of several 2-oxoacid-dependent dioxygenases involved in cell signalling and the activation of transcription factors open new fascinating perspectives for further research. |
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Authors:
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M C De Tullio; O Arrigoni |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cellular and molecular life sciences : CMLS Volume: 61 ISSN: 1420-682X ISO Abbreviation: Cell. Mol. Life Sci. Publication Date: 2004 Jan |
Date Detail:
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Created Date: 2004-01-27 Completed Date: 2004-03-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9705402 Medline TA: Cell Mol Life Sci Country: Switzerland |
Other Details:
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Languages: eng Pagination: 209-19 Citation Subset: IM |
Affiliation:
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Dipartimento di Biologia e Patologia Vegetale, Università di Bari, Via E. Orabona 4, 70125 Bari, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Ascorbic Acid / metabolism* Dehydroascorbic Acid / metabolism* Free Radicals / metabolism Humans Oxidation-Reduction Plant Physiological Phenomena |
| Chemical | |
Reg. No./Substance:
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0/Free Radicals; 490-83-5/Dehydroascorbic Acid; 50-81-7/Ascorbic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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