Document Detail

Honeycomb cysts in idiopathic pulmonary haemosiderosis: high-resolution CT appearances in two adults.
MedLine Citation:
PMID:  19029052     Owner:  NLM     Status:  MEDLINE    
Idiopathic pulmonary haemosiderosis (IPH) is characterized by recurrent episodes of pulmonary haemorrhage. The disease predominates in childhood, with approximately 20% of patients presenting in adulthood. Most patients present with dyspnoea, fatigue and recurrent haemoptysis, resulting in iron deficiency anaemia. High-resolution CT manifestations of IPH include patchy or diffuse ground glass opacity and consolidation resulting from alveolar haemorrhage. We describe a new high-resolution CT finding in two adults with IPH - multiple honeycomb cysts, which were characteristically focal and localized predominantly to the posterior and lateral basal segments. We suggest that the development of honeycombing in patients with IPH is a traction phenomenon resulting from recurrent haemosiderin deposition in the interstitium, which is known to lead to progressive fibrosis. These honeycomb cysts may indicate the sites of the most severe and recurrent alveolar haemorrhage in adults with IPH.
S Harte; W T McNicholas; S C Donnelly; J D Dodd
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of radiology     Volume:  81     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  e295-8     Citation Subset:  AIM; IM    
Department of Radiology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
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MeSH Terms
Cysts / radiography*
Hemoptysis / etiology
Hemosiderosis / complications,  radiography*
Lung Diseases / complications,  radiography*
Tomography, X-Ray Computed

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