Document Detail


Homozygous beta thalassemia in an African-American pediatric patient.
MedLine Citation:
PMID:  9484118     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Homozygous beta-thalassemia in an African-American pediatric patient is rare. In homozygous, beta-thalassemia there are characteristic changes due to severe chronic hemolytic anemia. Orofacial characteristics of homozygous beta-thalassemia result from expansion of bone marrow causing skull and facial deformities. This expansion causes clinically recognizable maxillary hyperplasia, severe protrusion of the middle third of the face, and anterior displacement of the incisors producing a typical faces historically referred to as "Cooley's face." The orofacial characteristics of an African American pediatric patient are described in detail.
Authors:
S DeBall; F M Gordy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of clinical pediatric dentistry     Volume:  21     ISSN:  1053-4628     ISO Abbreviation:  J Clin Pediatr Dent     Publication Date:  1997  
Date Detail:
Created Date:  1998-03-13     Completed Date:  1998-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9100079     Medline TA:  J Clin Pediatr Dent     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-9     Citation Subset:  D    
Affiliation:
Department of Pediatric Dentistry, University of Mississippi School of Dentistry, Jackson 39216, USA.
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group
Child
Child Behavior
Dental Care for Chronically Ill
Facial Bones / abnormalities
Facies*
Homozygote
Humans
Male
Malocclusion / etiology
Maxillofacial Abnormalities / etiology,  pathology*
beta-Thalassemia / complications,  genetics,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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