| Homocysteine as a risk factor for cardiovascular disease. | |
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MedLine Citation:
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PMID: 21239303 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Homocysteine is an amino acid that appears to damage the vascular endothelium and promote thrombosis. The most frequent causes of hyperhomocyst(e)inemia are the inherited defect of the enzyme cystathinonine B-synthase and nutritional deficiency of vitamin B(12) or folate. Hyperhomocyst(e)inemia is associated, perhaps causally, with atherosclerotic vascular disease. Interactions with risk factors such as cigarette smoking, hyperlipidemia, and hypertension are possible, but not yet defined. Dietary supplementation with vitamin B(12), folate, and other substances can reduce homocysteine levels. Such simple measures may reduce the risk of vascular disease in hyperhomocyst(e)inemic subjects. |
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Authors:
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I M Graham |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Trends in cardiovascular medicine Volume: 1 ISSN: 1050-1738 ISO Abbreviation: Trends Cardiovasc. Med. Publication Date: 1991 Sep |
Date Detail:
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Created Date: 2011-01-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108337 Medline TA: Trends Cardiovasc Med Country: United States |
Other Details:
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Languages: eng Pagination: 244-9 Citation Subset: - |
Copyright Information:
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Copyright © 1991. Published by Elsevier Inc. |
Affiliation:
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Department of Cardiology, Adelaide Hospital, Dublin, Ireland. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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