Document Detail

Home blood pressure has a stronger association with arterial stiffness than clinic blood pressure: the Finn-Home Study.
MedLine Citation:
PMID:  19745724     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Most of the earlier studies assessing the determinants of pulse wave velocity (PWV) have been conducted with conventional clinic blood pressure (BP) measurements. The aim of this study was to assess whether PWV is more strongly associated with home-measured BP than clinic BP. Other risk factors associated with PWV were also investigated. METHODS: The study population was an unselected sample of 237 adults aged 45-74 years. The study participants underwent the measurement of PWV, clinic BP (mean of two measurements using a mercury sphygmomanometer) and home BP (mean of 14 duplicate measurements during 1 week using a validated, automatic device). Fasting blood samples for serum lipids and glucose were drawn. RESULTS: Pearson's correlation coefficients for PWV and home/clinic BP differed significantly in favour of home measurement for systolic BP (0.65 vs. 0.50, P < 0.001), diastolic BP (0.51 vs. 0.37, P < 0.001) and pulse pressure (0.62 vs. 0.40, P < 0.001). In a linear regression model (R(2) = 0.60, P < 0.001), home systolic BP (P < 0.001), age (P < 0.001) and diabetes (P < 0.001) were independently associated with increased PWV. The association between home BP and PWV increased only slightly with the number of home measurements. CONCLUSION: Home BP is one of the most important factors affecting arterial stiffness, a strong predictor of cardiovascular risk. Home-measured BP is more strongly associated with PWV than is clinic BP, even for a low number of measurements. These data support the application of home BP measurement in clinical practice, as it seems to produce values that represent true BP better than clinic BP.
Teemu J Niiranen; Antti M Jula; Ilkka M Kantola; Mika K??h??nen; Antti Reunanen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Blood pressure monitoring     Volume:  14     ISSN:  1473-5725     ISO Abbreviation:  Blood Press Monit     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606438     Medline TA:  Blood Press Monit     Country:  England    
Other Details:
Languages:  eng     Pagination:  196-201     Citation Subset:  IM    
Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki/Turku, Finland.
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MeSH Terms
Ambulatory Care Facilities
Arteries / physiopathology*
Blood Flow Velocity / physiology
Blood Pressure / physiology*
Blood Pressure Determination / methods*
Cardiovascular Diseases / etiology
Middle Aged
Pulsatile Flow / physiology
Self Care*

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