Document Detail


Holmes tremor: Application of modern neuroimaging techniques.
MedLine Citation:
PMID:  17013902     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Holmes tremor has a characteristic rest, intention, and postural component. The syndrome arises as a consequence of a lesion in the upper brainstem and cerebral peduncles, which, it is postulated, interrupts the cerebello-rubrothalamic pathway. Ataxia, ophthalmoplegia, and bradykinesia are associated features. We present a case of Holmes tremor secondary to a midbrain cavernoma. Modern neuroimaging techniques in this case confirm that a combination of damage to the cerebello-rubrothalamic pathway and the nigrostriatal pathway is required for the full Holmes tremor syndrome to occur.
Authors:
Dominic C Paviour; H Rolf Jäger; Leonora Wilkinson; Marjan Jahanshahi; Andrew J Lees
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  21     ISSN:  0885-3185     ISO Abbreviation:  Mov. Disord.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-27     Completed Date:  2007-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2260-2     Citation Subset:  IM    
Copyright Information:
Copyright 2006 Movement Disorder Society.
Affiliation:
The Sara Koe PSP Research Centre, The Institute of Neurology, UCL, London, United Kingdom. dpaviour@dementia.ion.ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / pathology*
Humans
Magnetic Resonance Imaging / methods*
Male
Tremor / diagnosis*

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