Document Detail


Holes and channels between the ventricles revisited.
MedLine Citation:
PMID:  25245518     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Although holes, or channels, between the ventricles are the commonest congenital cardiac malformations, there is still no consensus as to how they can best be described and categorised. So as to assess whether it is possible to produce a potentially universally acceptable system, we have analysed the hearts categorised as having ventricular septal defects in a large archive held at Birmingham Children's Hospital. Materials and methods We analysed all the hearts categorised as having isolated ventricular septal defects, or those associated with aortic coarctation or interruption in the setting of concordant ventriculo-arterial connections, in the archive of autopsied hearts held at Birmingham Children's Hospital, United Kingdom.
RESULTS: We found 147 hearts within the archive fulfilling our criterions for inclusion. All could be classified within one of three groups depending on their borders as seen from the right ventricle. To provide full description, however, it was also necessary to take account of the way the defects opened to the right ventricle, and the presence or absence of alignment between the septal components.
CONCLUSIONS: By combining information on the phenotypic specificity defined on the basis of their borders, the direction of opening into the right ventricle, and the presence or absence of septal malalignment, it proved possible to categorise all hearts examined within the archive of Birmingham Children's Hospital. Our findings have necessitated creation of new numbers within the European Paediatric Cardiac Code.
Authors:
Adrian Crucean; William J Brawn; Diane E Spicer; Rodney C Franklin; Robert H Anderson
Related Documents :
25322898 - Anaesthetics as cardioprotectants - translatability and mechanism.
22499978 - Response to heart failure therapy: ventricular volume changes vs. shape changes.
25360388 - Heart failure with preserved ejection fraction - unwinding the diagnosis mystique.
511298 - Permeability factor contaminating hyaluronidase preparations.
696328 - Experimental endocarditis in rabbits. i. technique and spontaneous course of non-bacter...
24529648 - Five-year outcomes for first generation drug-eluting stents versus bare-metal stents in...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-23
Journal Detail:
Title:  Cardiology in the young     Volume:  -     ISSN:  1467-1107     ISO Abbreviation:  Cardiol Young     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-23     Completed Date:  -     Revised Date:  2014-9-24    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-12     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Chikungunya in the Caribbean: An Epidemic in the Making.
Next Document:  Effects of Using Nintendo Wii™ Exergames in Older Adults: A Review of the Literature.