Document Detail

Hodgkin's lymphoma-related vanishing bile duct syndrome: A case report and literature review.
MedLine Citation:
PMID:  24183359     Owner:  NLM     Status:  In-Data-Review    
We report the case of a 38-year-old man who developed vanishing bile duct syndrome in association with Hodgkin's lymphoma. He was noted to have cervical lymphadenopathy and marked elevation of total serum bilirubin at diagnosis. He achieved complete remission with normalization of serum bilirubin after eight courses of Adriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy followed with autologous hematopoietic cell transplantation. Consecutive liver biopsies performed at diagnosis and at the stage of complete remission revealed the disappearance and regeneration of interlobular bile ducts, respectively. Our case provides pathological evidence that Hodgkin's lymphoma-related vanishing bile duct syndrome is a reversible bile duct injury disease. Bilirubin is a reliable serum marker to monitor the treatment response of these cases. The mechanism to develop hyperbilirubinemia with vanishing bile duct in such a case of Hodgkin's lymphoma remains to be studied. A literature review was carried out.
Kiong-Ming Wong; Chao-Sung Chang; Chun-Chieh Wu; Hsin-Ling Yin
Related Documents :
6490929 - Paradoxical procedures and single-case methodology: review and recommendations.
20606989 - Intraoral approach: a newer technique for filler injection.
7436269 - Transplantation of the cryopreserved nipple-areolar complex.
531619 - Treatment of severe spondylolisthesis. a combined approach for reduction and stabilizat...
20697319 - Do not use epinephrine in digital blocks: myth or truth? part ii. a retrospective revie...
8592319 - Conservative management of incidental cystotomy at laparoscopy. a report of two cases.
23966809 - Treatment of childhood psoriasis with phototherapy and photochemotherapy.
16381139 - Myxolipoma of the epiglottis in an adult: a case report.
10458839 - Benign fibroepithelial polyps of the renal pelvis.
Publication Detail:
Type:  Journal Article     Date:  2013-08-09
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  29     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  636-41     Citation Subset:  IM    
Copyright Information:
Copyright © 2013. Published by Elsevier B.V.
Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Perceptions on gender awareness and considerations in career choices of medical students in a medica...
Next Document:  Diffuse malignant peritoneal mesothelioma.