Document Detail

Hodgkin's lymphoma presenting as extradural spinal cord compression.
MedLine Citation:
PMID:  14719584     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Hodgkin's lymphoma presenting with spinal cord compression is rare. Reports estimate that only 5% of patients with Hodgkin's lymphoma have spinal cord compression. The objectives of this study were:- (1) To review the histology of all cases of Hodgkin's lymphoma causing spinal cord compression. (2) To correlate the findings with the clinical details- lymphadenopathy, hepatosplenomegaly, and marrow involvement. METHOD: This was a retrospective study, the period of study being between 1987-2002. All cases were taken from the histopathology record files, pathology department, NIMS, Hyderabad. The clinical profile of each case was noted and the histology reviewed. When necessary, immunohistochemistry with the necessary markers was performed. RESULT: There were 12 cases, of which 11 were males, and one was a female. The patients ranged from 8-62 years of age, with a median age of 32 years. The cord involvement was at different levels- thoracic(8), lumbar(2) and cervical(2). CONCLUSIONS: The histologic diagnosis of Hodgkin's lymphoma presenting as cord compression requires awareness of the condition. The close differential diagnoses include non-specific inflammation, non-Hodgkin's lymphoma, tuberculosis and eosinophilic granuloma. Detailed clinical evaluation is essential for interpreting the histology.
T Roshni Paul; C Sundaram; A K Reddy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  51     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2004-01-14     Completed Date:  2004-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  960-2     Citation Subset:  IM    
Department of Pathology and Neurosurgery, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad 500082.
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MeSH Terms
Hodgkin Disease / complications*,  diagnosis
Middle Aged
Retrospective Studies
Spinal Cord Compression / etiology*

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