| Hodgkin's lymphoma associated with plasma cell neoplasia: cytological features and review of the literature. | |
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MedLine Citation:
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PMID: 16078251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hodgkin's lymphoma (HL) associated with plasma cell neoplasia is extremely rare. Here, we report one case diagnosed by fine-needle aspiration biopsy (FNAB) and review the clinical features of 15 previously reported cases. Our specimen was obtained by FNAB of an enlarged right inguinal lymph node. Air-dried Diff-Quik (DQ)-stained slides and alcohol-fixed slides stained with hematoxylin-eosin (H&E) and Papanicolaou stains were reviewed. The specimen was cellular, consisting of lymphocytes and plasma cells. Flow cytometric analysis revealed a monoclonal (M) plasma-cell population. Admixed large atypical mono- and binucleated cells immunoreactive for CD30 were noted also. A diagnosis of plasma-cell neoplasm associated with classic HL was confirmed histologically after surgical removal of the lymph node. The diagnosis of both HL and plasma-cell neoplasia in the same patient is exceedingly rare. Adding another case to the 15 previously reported cases was unique because our case was diagnosed through FNAB. |
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Authors:
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Bahram R Oliai; Maureen F Zakowski; Oscar Lin |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diagnostic cytopathology Volume: 33 ISSN: 8755-1039 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-08-12 Completed Date: 2005-11-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: United States |
Other Details:
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Languages: eng Pagination: 181-6 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2005 Wiley-Liss, Inc. |
Affiliation:
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Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Fine-Needle Hodgkin Disease / metabolism, pathology* Humans Immunohistochemistry Lymph Nodes / metabolism, pathology* Male Middle Aged Neoplasms, Multiple Primary / metabolism, pathology* Plasmacytoma / metabolism, pathology* Tumor Markers, Biological / analysis |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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