Document Detail

Hodgkin's disease: a flow cytometric study.
MedLine Citation:
PMID:  3366919     Owner:  NLM     Status:  MEDLINE    
Flow cytometry was performed on paraffin embedded tissue from 115 cases of Hodgkin's disease. Thirteen (11%) tumours were aneuploid with no significant difference between the histological subgroups. The median proliferative index was 14%, and the highest values were found in the NS2 (16.4%) and lymphocyte depleted (16.0%) subgroups. The difference in proliferative index approached significance when the NS2 subgroup was compared with the NS1 subgroup (p less than or equal to 0.11) and when the lymphocyte depleted and NS2 subgroups combined were compared with the mixed cellularity, lymphocyte predominance, and NS1 subgroups combined (p less than or equal to 0.07). There was a trend towards better survival for patients with aneuploid tumours and those cases with a proliferative index below 15%, but neither of these trends was significant.
K G Morgan; P Quirke; C J O'Brien; C C Bird
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  41     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-06-20     Completed Date:  1988-06-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  365-9     Citation Subset:  AIM; IM    
Department of Pathology, University of Leeds.
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MeSH Terms
Aged, 80 and over
Child, Preschool
DNA, Neoplasm / analysis*
Flow Cytometry
Hodgkin Disease / analysis,  mortality,  pathology*
Middle Aged
Reg. No./Substance:
0/DNA, Neoplasm

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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