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Hodgkin lymphoma mortality in the Americas, 1997-2008: Achievements and persistent inadequacies.
MedLine Citation:
PMID:  23335127     Owner:  NLM     Status:  Publisher    
Although therapeutic advancements have made Hodgkin lymphoma (HL) a largely curable disease, trends in HL mortality have been variable across countries. To provide updated information on HL mortality in the Americas, overall and 20 to 44 years age-standardized (world population) mortality rates from HL were derived for the 12 Latin American countries providing valid data to the WHO database and with more than 2 million of inhabitants. For comparative purpose, data for the USA and Canada were also presented. Trends in mortality over the period 1997-2008 are based on joinpoint regression analysis. Declines in HL mortality were registered in all Latin American countries except in Venezuela. In most recent years, HL mortality had fallen to about 0.3/100,000 men and 0.2/100,000 women in Argentina, Brazil, Chile, Colombia, Ecuador and Guatemala, i.e., to values similar to North America. Despite some declines, rates remained high in Cuba (1/100,000 men and 0.7/100,000 women), in Costa Rica and Mexico as well as Venezuela (between 0.5 and 0.6/100,000 men and between 0.3 and 0.5/100,000 women). In young adults, trends were favorable in all Latin American countries except Cuba, whose rates remained exceedingly high (0.8/100,000 men, 0.6/100,000 women). Thus, appreciable declines in HL mortality were observed in most Latin America over the last decade, and several major countries reached values comparable to North America. Substantial excesses mortality were still observed in Cuba, Costa Rica, Mexico and Venezuela, calling for urgent interventions to improve HL management of in those countries.
Liliane Chatenoud; Paola Bertuccio; Cristina Bosetti; Teresa Rodriguez; Fabio Levi; Eva Negri; Carlo La Vecchia
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-21
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  -     ISSN:  1097-0215     ISO Abbreviation:  Int. J. Cancer     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 UICC.
Department of Epidemiology Istituto di Ricerche Farmacologiche "Mario Negri", Via G. La Masa 19, 20156 Milan, Italy.
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