Document Detail


History of abortion, preterm and term birth, and risk of gestational hypertension: a population-based study.
MedLine Citation:
PMID:  15603101     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the consequence of prior abortion and preterm and term birth on the occurrence of gestational hypertension in the subsequent pregnancy. STUDY DESIGN: A population-based, retrospective, cohort study was conducted based on 140,773 pregnancies delivered between 1993 and 1999 in 49 hospitals in northern and central Alberta, Canada. Multivariate logistic regression was applied to estimate ORs with 95% CIs, adjustedfor confounding variables. RESULTS: The incidence of gestational hypertension was markedly lower in women who previously delivered at term than in primigravid women (2.4% vs. 5.6%) (adjusted OR [aOR]: .41 [.38-.44], p < 0.001). The incidence of gestational hypertension in women with previous preterm birth but without prior abortion or term pregnancy was also lower than in primiparous women (3.9% vs. 5.6%) (aOR: .72 [.54-.95], p<0.05). Moreover, there was a trend toward a decreased incidence of gestational hypertension among women with a longer duration of previous preterm gestation. Although there was a statistically significant decreased incidence of gestational hypertension in pregnancies in women with a previous history of abortion (4.9%) as compared to women without such a history (5.6%) (aOR:.85[95% CI: .77-.93], p < 0.05), 2, 3 or more abortions were not associated with a decreased risk of gestational hypertension, calling into question the clinical significance of the effect of abortion. CONCLUSION: There was a trend toward a decreased incidence of gestational hypertension among women with a longer duration of previous gestation. However, a history of term pregnancy (> or =37 weeks) conveyed the most substantial protection against gestational hypertension in the subsequent pregnancy.
Authors:
Xu Xiong; William D Fraser; Nestor N Demianczuk
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  49     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-17     Completed Date:  2005-02-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  899-907     Citation Subset:  IM    
Affiliation:
Departments of Obstetrics and Gynecology, University of Montreal, Quebec, Canada. xxiong@tulane.edu
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MeSH Terms
Descriptor/Qualifier:
Abortion, Induced / adverse effects*
Adolescent
Adult
Cohort Studies
Female
Humans
Hypertension, Pregnancy-Induced / epidemiology,  etiology*
Incidence
Medical History Taking
Odds Ratio
Pregnancy
Premature Birth*
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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