Document Detail


The History of Progesterone.
MedLine Citation:
PMID:  23974783     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Progesterone, the principal pregestational hormone of the body, is metabolized and produced in the corpus luteum via conversion of pregnenolone. Progesterone functions to prepare the uterus for the reception and development of the fertilized ovum by transformation of the endometrium from the proliferative to the secretory stage. By suppressing menstruation and uterine contractility, progesterone is extremely important in the maintenance of pregnancy. The two most frequent uses for progestins are contraception and hormone replacement therapy. This article provides a brief history of the discovery of progesterone and its therapeutic development and discusses the major challenges and advancements in steroid chemistry.
Authors:
Stephen J Newton
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  International journal of pharmaceutical compounding     Volume:  11     ISSN:  1092-4221     ISO Abbreviation:  Int J Pharm Compd     Publication Date:    2007 July-Aug
Date Detail:
Created Date:  2013-8-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706294     Medline TA:  Int J Pharm Compd     Country:  -    
Other Details:
Languages:  ENG     Pagination:  274-277     Citation Subset:  -    
Affiliation:
Spectrum Pharmacy Products, Inc., Tucson, Arizona.
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