Document Detail

Historical vignette celebrating the 30th anniversary of diagnostic ambulatory electrocardiographic monitoring and data reduction systems.
MedLine Citation:
PMID:  1987237     Owner:  NLM     Status:  MEDLINE    
The ambulatory electrocardiographic (ECG) monitor is a device developed approximately 30 years ago to detect, locate and document hemodynamic insufficiency states in target organs with compromised regional arterial circulations. These insufficiency states are usually silent until they are suddenly precipitated by secondary remote, hemodynamically significant cardiac arrhythmias, hypotensive states caused by internal hemorrhage or reduced cardiac output including cardiogenic shock. Insufficiency events cause serious regional dysfunction, resulting in transitory or permanent damage of the remote target organs (brain, heart, splanchnic and renal) often causing paralytic ileus, gangrene of the gut or rectum, myocardial infarction or cerebral stroke. Comprehensive experimental studies conducted in the author's laboratory over a period of years (1946-1971) proved that such remote ischemic states are often recurrent and can cause serious, irreparable damage, but whenever the cause of the regional ischemic state was treated promptly it could reverse the insufficiency state. Practical ambulatory ECG diagnostic monitors and data reduction systems were developed to diagnose these elusive precipitating pathophysiologic events that might coincide with the patient's symptoms and thus determine the most appropriate preventive therapy.
E Corday
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Publication Detail:
Type:  Biography; Historical Article; Journal Article; Portraits    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  17     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1991 Jan 
Date Detail:
Created Date:  1991-02-21     Completed Date:  1991-02-21     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  286-92     Citation Subset:  AIM; IM; Q    
Cedars-Sinai Medical Center, Los Angeles, California 90048.
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MeSH Terms
Electrocardiography, Ambulatory / history*
History, 20th Century
United States
Personal Name Subject
Personal Name Subject:
N J Holter; E Corday
Comment In:
J Am Coll Cardiol. 1991 Oct;18(4):1147   [PMID:  1894859 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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