Document Detail

Historical perspective: surgery for chronic thromboembolic disease.
MedLine Citation:
PMID:  10378858     Owner:  NLM     Status:  MEDLINE    
Obstruction of major pulmonary vessels with organized thromboemboli is a rare sequelae of acute pulmonary embolic disease. Depending on the extent and duration of vascular occlusion, patients experiencing this unusual disorder may develop significant pulmonary hypertension and cor pulmonale. If left untreated, the ultimate clinical outcome is right heart failure and death. Over the past several decades, the description of this clinical entity has evolved from an autopsy curiosity to a recognized cause of chronic pulmonary hypertension. Also, during this same time period, surgical capabilities have greatly advanced, providing these patients a potentially life-saving remedy for this debilitating form of pulmonary vascular disease. This article provides a historical perspective for our current understanding of major vessel chronic thromboembolic pulmonary hypertension as a distinct clinical disorder. It also chronicles the developments in surgical techniques that have made thromboendarterectomy of the pulmonary arterial bed a reality.
P O Daily; W R Auger
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Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  Seminars in thoracic and cardiovascular surgery     Volume:  11     ISSN:  1043-0679     ISO Abbreviation:  Semin. Thorac. Cardiovasc. Surg.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-08-05     Completed Date:  1999-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8917640     Medline TA:  Semin Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  143-51     Citation Subset:  IM; Q    
Division of Cardiac Surgery, Sharp Memorial Hospital, San Diego, CA, USA.
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MeSH Terms
Chronic Disease
Endarterectomy / history*
History, 20th Century
Hypertension, Pulmonary / history*,  surgery
Pulmonary Artery / surgery*
Pulmonary Embolism / history*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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