| Historical developments and perspectives in inorganic fiber toxicity in man. | |
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MedLine Citation:
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PMID: 2272322 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The first patient known to have died from asbestosis (1900) began work in 1885, approximately 5 years after the industrial use of asbestos began in Britain. Mineral particles were found in his lungs. No special comment was made of their fibrous nature then nor when the first case was reported in 1924. The various neoplasms attributed to asbestos in the next decades posed an additional question: What influence did the fibrous shape of the particles have on carcinogenic potential? The cogency of the problem was amplified by the identification in humans of asbestos-like neoplasms with a fiber other than asbestos (erionite) and by the production of such neoplasms in experimental animals with a variety of man-made inorganic fibers, often used as substitutes for asbestos. The lessons learned about asbestos may help guide us in evaluating current fiber problems. |
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Authors:
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I J Selikoff |
Publication Detail:
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Type: Historical Article; Journal Article; Review |
Journal Detail:
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Title: Environmental health perspectives Volume: 88 ISSN: 0091-6765 ISO Abbreviation: Environ. Health Perspect. Publication Date: 1990 Aug |
Date Detail:
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Created Date: 1991-02-28 Completed Date: 1991-02-28 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0330411 Medline TA: Environ Health Perspect Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 269-76 Citation Subset: IM; Q |
Affiliation:
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Mount Sinai School of Medicine, City University of New York, NY 10029. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Air Pollutants, Occupational
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adverse effects Asbestos / adverse effects, chemistry Asbestosis / etiology, history* Dust / adverse effects History, 19th Century History, 20th Century Humans Models, Biological Occupational Diseases / diagnosis, etiology, prevention & control Particle Size Risk Factors |
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Reg. No./Substance:
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0/Air Pollutants, Occupational; 0/Dust; 1332-21-4/Asbestos |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): Environ Health Perspect ISSN: 0091-6765 |
Article Information Download PDF  Print publication date: Month: 8 Year: 1990 Volume: 88First Page: 269 Last Page: 276 ID: 1567992 PubMed Id: 2272322 |
| Historical developments and perspectives in inorganic fiber toxicity in man. | |
| I J Selikoff | |
| Mount Sinai School of Medicine, City University of New York, NY 10029. |
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