Document Detail

Histopathology report of cutaneous melanoma and sentinel lymph node in Europe: a web-based survey by the Dermatopathology Working Group of the European Society of Pathology.
MedLine Citation:
PMID:  19352698     Owner:  NLM     Status:  MEDLINE    
In order to survey the diagnostic reporting of melanomas by European pathologists and assess their current practice and opinions on the information required in the final report, a web-based questionnaire was diffused through the members of the Dermatopathology Working Group of the European Society of Pathology. Forty replies from different pathology laboratories were collected (49%). Main prognostic parameters related to the primary tumor, including Breslow thickness, presence of ulceration, and Clark's level, as well as additional features, are reported by a large majority of laboratories. Presence of regression is reported by 90% of respondents but with different recording items. For sentinel lymph node (SLN) biopsy for melanoma, the conventional panel of antibodies includes S-100, Melan A, and HMB45. Dissection of the SLN is performed by "bivalve" or "bread loaf" approach. The number of sections cut and stained varies. Forty-four percent of respondents report depths of metastases from the capsule, while the majority report maximum dimension of the largest deposit. Results indicate that pathology reports for primary cutaneous melanoma and SLN vary between laboratories across Europe. Although the most important prognostic features are universally reported, key features which impact on prognosis and treatment are often omitted and others still require standardization.
Anna Batistatou; Martin G Cook; Daniela Massi;
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Publication Detail:
Type:  Journal Article     Date:  2009-04-08
Journal Detail:
Title:  Virchows Archiv : an international journal of pathology     Volume:  454     ISSN:  0945-6317     ISO Abbreviation:  Virchows Arch.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-30     Completed Date:  2009-07-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423843     Medline TA:  Virchows Arch     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  505-11     Citation Subset:  IM    
Department of Pathology, University of Ioannina, Medical School, University Campus, P.O. Box 1186, 451 10, Ioannina, Greece.
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MeSH Terms
Disease Progression
Health Care Surveys
Lymph Nodes / pathology
Lymphatic Metastasis / diagnosis
Medical Records / standards
Melanoma / secondary*
Professional Practice
Sentinel Lymph Node Biopsy
Skin Neoplasms / pathology*
Societies, Medical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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