Document Detail

Histopathology of gills in mosquitofish, Gambusia affinis after long-term exposure to sublethal concentrations of malathion.
MedLine Citation:
PMID:  12929717     Owner:  NLM     Status:  MEDLINE    
The histopathological effects of malathion, an organophosphate pesticide, on the gill tissues in mosquitofish, Gambusia affinis, were determined by light microscope. The fish were exposed to sublethal concentrations (0.01 and 0.02 mg/L) of malathion for 10, 20 and 30 days. Histological examination of the gills treated with malathion showed a variety of histopathological effects. The gill lesions included necrosis and desquamation of secondary lamellar epithelium, lifting up of epithelium, intraepithelial oedema, fusion of adjacent secondary lamellae, haemorrhage at primary lamellae, disorganization and rupture in seconder lamellae, hypertrophy and hyperplasia of epithelial cells. These alterations were time- and dose-dependent.
E I Cengiz; E Unlü
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes     Volume:  38     ISSN:  0360-1234     ISO Abbreviation:  J Environ Sci Health B     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-21     Completed Date:  2003-12-23     Revised Date:  2009-07-21    
Medline Journal Info:
Nlm Unique ID:  7607167     Medline TA:  J Environ Sci Health B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  581-9     Citation Subset:  IM    
Department of Biology, Faculty of Science and Art, Dicle University, Diyarbakir, Turkey.
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MeSH Terms
Dose-Response Relationship, Drug
Gills / drug effects,  pathology*
Insecticides / toxicity*
Malathion / toxicity*
Time Factors
Water Pollutants, Chemical / toxicity*
Reg. No./Substance:
0/Insecticides; 0/Water Pollutants, Chemical; 121-75-5/Malathion

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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