Document Detail

Histopathology of the conduction system in patients with atrioventricular or intraventricular conduction disturbances.
MedLine Citation:
PMID:  139819     Owner:  NLM     Status:  MEDLINE    
In 9 lethal cases where clinical signs gave rise to the suspicion of acute myocardial infarct (AMI) where well-characterized e.c.g.-changes, permanent or intermittent, were found by monitoring, a very careful autopsy of the heart was carried out, combined with a meticulous histological investigation of the conduction system. Acute changes of mild degree in the conduction system were found only in one case, possibly explaining the left bundle branch block found in this case. In the remaining cases, nothing but chronic changes were found and they did not exceed significantly the changes otherwise to be found in the agegroups concerned in a "control series" of violent deaths not preceded by symptoms of heart disease. According to an estimate there was good correlation between the conduction disturbances demonstrated and the localization of histopathological changes in seven of nine patients; in one of the latter correlation was relatively good; correlation was dubious only in one case. On this basis the authors conclude that present changes in the conduction system which are assumed mainly to be age-related, are the factors to determine the type of conduction disturbances from which the patient will suffer if acute heart ischaemia sets in, for instance due to an AMI, in fact, changes by which he will be predisposed to such disturbances.
J Voigt; E Steinmetz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta pathologica et microbiologica Scandinavica. Section A, Pathology     Volume:  85A     ISSN:  0365-4184     ISO Abbreviation:  Acta Pathol Microbiol Scand A     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-05-12     Completed Date:  1977-05-12     Revised Date:  2009-06-04    
Medline Journal Info:
Nlm Unique ID:  7508468     Medline TA:  Acta Pathol Microbiol Scand A     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  174-82     Citation Subset:  IM    
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MeSH Terms
Bundle-Branch Block / pathology*
Cardiomegaly / pathology
Coronary Vessels / pathology
Heart Block / pathology*
Heart Conduction System / pathology*
Heart Ventricles / pathology
Middle Aged
Myocardial Infarction / pathology
Myocardium / pathology*
Organ Size

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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