Document Detail

Histopathological verification for successful ablation of mitral isthmus ventricular tachycardia complicated with cardiac sarcoidosis.
MedLine Citation:
PMID:  22293803     Owner:  NLM     Status:  In-Data-Review    
A 68-year-old man died a few days after catheter ablation of drug-resistant, monomorphic ventricular tachycardia (VT) complicated with cardiac sarcoidosis. The diagnosis of mitral isthmus VT was made from electrophysiological observations, including electro-anatomical activation and voltage map, pace-mapping, entrainment mapping and ablation outcome. On autopsy of the heart, sarcoidic lesion with scattered fibrous tissue in the mitral isthmus was non-transmural, and the surviving myocardium serving as the reentry circuit in the endomyocardium was isolated from the adjacent viable epimyocardium, enabling the sustenance of macroreentry across the mitral isthmus. Non-transmural lesions produced by RF delivery created a barrier sufficient to interrupt the myocardial bundles located in the mitral isthmus, eliminating the mitral isthmus VT.
Yoshiaki Kaneko; Osamu Igawa; Tadanobu Irie; Masamitsu Adachi; Tadashi Nakajima; Hideaki Yokoo; Yoichi Nakazato; Masahiko Kurabayashi
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Publication Detail:
Type:  Journal Article     Date:  2012-02-01
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  281-5     Citation Subset:  IM    
Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Japan.
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