| Histopathological sinus node classification and its relation to coronary atherosclerosis using an atherometric system. | |
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MedLine Citation:
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PMID: 2327187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies were conducted into 100 consecutive subjects (autopsy material), 53 men and 43 women between 31 and 70 years old, who had died a natural death. The HUDSON-procedure was used for histopathological analysis of the cardiac conducting system (CCS). About 48 microscopic slides of each subject, including sinus node (SN) tissue, were inspected by 4 pathologists in a blind study. The findings were classified by 3 different groups according to histopathological data of the SN, viz. changes and distribution of P and T cells, stroma, artery, and innervation of SN. The 3 major epicardial branches of coronary arteries were prepared for morphometric studies by WHO standards. A digitizer coupled to a microcomputer LTEL (Cuba, IBM-compatible) was used for quantitative evaluation of atherosclerotic lesions (AL), and all data were subsequently processed on the same computer, using a statistical commercial package (Number Cruncher Statistical System) for results. An atherometric system was used and proved to be a properly standardized methodology, suitable to characterize AL in any vascular sector or group of patients. The most remarkable results were as follows: Three-group classification was useful in estimating the association between pathomorphological data of SN and coronary atherosclerosis. The atherometric system proved to be a powerful tool to study and characterize atherosclerotic lesions in coronary arteries. |
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Authors:
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J E Fernández-Britto; A M Vikhert; A Paramio; R Campos; R Wong; D Madan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Zentralblatt für allgemeine Pathologie und pathologische Anatomie Volume: 136 ISSN: 0044-4030 ISO Abbreviation: Zentralbl Allg Pathol Publication Date: 1990 |
Date Detail:
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Created Date: 1990-05-14 Completed Date: 1990-05-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9105593 Medline TA: Zentralbl Allg Pathol Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 77-86 Citation Subset: IM |
Affiliation:
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Department of Pathology, Dr. Carlos J. Finlay Hospital, Havana, Cuba. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Artery Disease / pathology* Coronary Vessels / pathology Female Humans Male Microcomputers Middle Aged Myocardial Infarction / pathology Sinoatrial Node / pathology* Software |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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