Document Detail


Histopathological features of bisphosphonate-associated osteonecrosis: findings in patients treated with partial mandibulectomies.
MedLine Citation:
PMID:  23159117     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The present study investigated the histopathologic and radiographic features of stage 3 bisphosphonate-associated osteonecrosis of the jaw (BAONJ) in patients who were treated with partial mandibulectomies. Bisphosphonates had been orally administered to 10 patients with osteoporosis and intravenously administered to 1 patient with metastatic carcinoma. On radiographic images, massive osteolysis and periosteal bone formations were conspicuous, and a thin mandibular cortical width was observed in 5 of 10 osteoporosis patients despite the previous use of bisphosphonate. Microscopically, the mandibulectomy specimens of the patients could be divided into 4 distinct layers. Although there were few differences in overall histologic features between BAONJ and chronic suppurative osteomyelitis, a notable number of osteoclasts were found detached from the bony trabeculae in BAONJ.
Authors:
Young-Ah Cho; Hye-Jung Yoon; Jae-Il Lee; Sam-Pyo Hong; Seong-Doo Hong
Related Documents :
24945187 - Physician global assessments or blood tests do not predict mucosal healing in ulcerativ...
24048117 - Ultrasound assessment of subcutaneous compressibility: a potential adjunctive diagnosti...
24719957 - Plasma levels of gastric biomarkers in patients after bariatric surgery: biomarkers aft...
24417817 - The rome iii criteria for the diagnosis of functional dyspepsia in secondary care are n...
11211167 - Changes in the use of medications after acute myocardial infarction: possible impact on...
24945187 - Physician global assessments or blood tests do not predict mucosal healing in ulcerativ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology and oral radiology     Volume:  114     ISSN:  2212-4411     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101576782     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  785-91     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Clinical Lecturer, Department of Oral Pathology, School of Dentistry, Seoul National University, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  BRAF and GNAQ mutations in melanocytic tumors of the oral cavity.
Next Document:  Incidental pneumoparotid detected on computed tomography: Should it raise an alarm?