Document Detail

Histopathological effects of bipolar vessel sealing devices on liver parenchyma and comparison with suture method: an experimental study.
MedLine Citation:
PMID:  17299268     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: LigaSureand SurgRx are bipolar vessel sealing devices providing hemostasis by denaturating collagen and elastin from the vessel wall and surrounding connective tissue. We aimed to histopathologically evaluate the lateral injury during rat liver resection with LigaSure and SurgRx. METHODS: Suture technique was used in group A, LigaSure was used in group B and SurgRx was used in group C to resect one lobe of liver from midline. One of the resected pieces was histopathologically examined the same day and the other piece was left in the animal to be examined at the 7th day. Relaparotomy was performed at the 7th day. RESULTS: Necrosis, exudate formation, chronic inflammation, histiocytes and fibroblasts scores were significantly lower in SurgRx group compared to the other groups. CONCLUSION: Our findings suggest that LigaSure and SurgRx can be safely used in liver resection as compared to suture technique while SurgRx was superior than LigaSure in inflammatory response as it causes lower lateral thermal injury and inflammatory scores probably due to its different technical properties.
D A Sahin; R Kusaslan; O Sahin; G Akbulut; O Bas; O N Dilek
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-02-13
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  39     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  2007  
Date Detail:
Created Date:  2007-03-30     Completed Date:  2007-05-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  111-7     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
Department of General Surgery, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
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MeSH Terms
Blood Loss, Surgical / prevention & control
Chronic Disease
Exudates and Transudates
Fibroblasts / pathology
Granulation Tissue / pathology
Hemostasis, Surgical / instrumentation*,  methods*
Hepatitis / pathology
Histiocytes / pathology
Liver / blood supply,  pathology*,  surgery*
Postoperative Complications / pathology
Rats, Sprague-Dawley
Suture Techniques*

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