Document Detail

Histopathological atlas of renal diseases: ANCA-associated vasculitis (first part).
MedLine Citation:
PMID:  15931638     Owner:  NLM     Status:  MEDLINE    
"ANCA-associated vasculitis" are Wegener's Granulomatosis, Micropolyarteritis and its renal-limited variant (previously called idiopathic necrotizing glomerulonephritis). According to the "Chapel Hill Consensus Conference" classification, ANCA-associated vasculitis are characterized by prevalent involvement of small-size vessels, whereas medium and large-size arteries involvement is the marker of Polyarteritis Nodosa. But the vessel size-based classification is not always powerful enough, because also in ANCA-associated vasculitis the involvement of medium and large-size arteries if frequent. The distinctive marker of ANCA-associated renal vasculitis has therefore become the presence of necrotizing extracapillary glomerulonephritis, that is always absent in Polyarteritis Nodosa.
Franco Ferrario; Maria Pia Rastaldi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of nephrology     Volume:  18     ISSN:  1121-8428     ISO Abbreviation:  J. Nephrol.     Publication Date:    2005 Mar-Apr
Date Detail:
Created Date:  2005-06-02     Completed Date:  2005-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  113-6     Citation Subset:  IM    
Renal Immunopathology Center, S. Carlo Borromeo Hospital and Nuova Nefrologia Research Association, Milan, Italy.
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MeSH Terms
Antibodies, Antineutrophil Cytoplasmic / analysis*
Biological Markers / analysis
Glomerulonephritis / pathology*
Polyarteritis Nodosa / pathology*
Wegener Granulomatosis / pathology*
Reg. No./Substance:
0/Antibodies, Antineutrophil Cytoplasmic; 0/Biological Markers

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