| Histone Variants and Transcription Regulation. | |
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MedLine Citation:
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PMID: 23150257 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Histones are the protein components of chromatin and are important for its organization and compaction. Although core histones are exclusively expressed during S phase of the cell cycle, there exist variants of canonical histones that are expressed throughout the cell cycle. These histone variants are often deposited at defined regions of the genome and they play important roles in a variety of cellular processes, such as transcription regulation, heterochromatin formation and DNA repair. In this chapter, we will focus on several histone variants that have been linked to transcription regulation, and highlight their physical and functional features that facilitate their activities in this context. |
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Authors:
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Cindy Law; Peter Cheung |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Sub-cellular biochemistry Volume: 61 ISSN: 0306-0225 ISO Abbreviation: Subcell. Biochem. Publication Date: 2013 |
Date Detail:
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Created Date: 2012-11-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0316571 Medline TA: Subcell Biochem Country: - |
Other Details:
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Languages: ENG Pagination: 319-341 Citation Subset: - |
Affiliation:
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Ontario Cancer Institute, 610 University Avenue, Toronto, ON, M5G 2M9, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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