Document Detail

Histology of air sac lesions induced in chickens by contact exposure to Mycoplasma synoviae.
MedLine Citation:
PMID:  969169     Owner:  NLM     Status:  MEDLINE    
Chickens were housed when 1 day old with chickens experimentally infected with Mycoplasma synoviae. Air sacs from 16 of the 2-week-old and eight of the 3-week-old contact-exposed chickens were given gross lesion scores and embedded in glycol methacrylate for slide preparation. Histologic lesions in air sacs with gross scores of 0-2 were mild edema resulting in a two to eightfold increase in air sac thickness, capillary proliferation, and exudate consisting largely of heterophils and necrotic debris. Histologic lesions in air sacs with gross scores of 3 and 4 were marked hyperplasia of epithelial cells and diffuse infiltration of the air sac connective tissue by mononuclear cells. Nine of 10 air sacs with gross scores of 0 had no histologic evidence of inflammation. The most severe histologic lesions were in those air sacs with gross scores of 4. The glycol methacrylate procedure resulted in 2-mum sections with excellent cellular detail.
O J Fletcher; D P Anderson; S H Kleven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary pathology     Volume:  13     ISSN:  0300-9858     ISO Abbreviation:  Vet. Pathol.     Publication Date:  1976  
Date Detail:
Created Date:  1976-11-21     Completed Date:  1976-11-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0312020     Medline TA:  Vet Pathol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  303-14     Citation Subset:  IM    
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MeSH Terms
Air Sacs / pathology*
Mycoplasma Infections / pathology,  veterinary*
Poultry Diseases / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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