Document Detail


Histological and ultrastructural aspects of the tongue in undernourished rats.
MedLine Citation:
PMID:  17143432     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The objective of this study is to verify the histological and ultrastructural aspects of the tongue mucosa in protein-caloric undernourished adult rats.
MATERIAL AND METHODS: A clinical experimental study was done in thirty Wistar rats, 15 controls and 15 with protein-caloric undernourishment. The last group received ration in small amounts, with a reduced casein content, during 45 days. Rats were weighed every 3 days, from the first (90 days of life) to the last day of a 45-day dietary period, when they were sacrificed. Plasma was used for protein electrophoresis and their tongues were prepared for light and scanning electron microscopy. Analyses of variance and Student's t-test were used for statistical analysis.
RESULTS: A significant decrease in weight and in plasma proteins was found in protein-caloric undernourished rats compared to the control group. Histological findings revealed no differences between the two groups and there were no statistically significant differences in the filiform papilla count under the scanning electron microscopy.
CONCLUSION: Protein-caloric undernourishment does not cause alterations in the tongue mucosa of adult rats.
Authors:
Marilda Aparecida Milanez Morgado de Abreu; Luc Louis Maurice Weckx; Cleonice Hitomi Watashi Hirata
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brazilian journal of otorhinolaryngology     Volume:  72     ISSN:  1808-8694     ISO Abbreviation:  Braz J Otorhinolaryngol     Publication Date:    2006 Jul-Aug
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-05-10     Revised Date:  2012-10-24    
Medline Journal Info:
Nlm Unique ID:  101207337     Medline TA:  Braz J Otorhinolaryngol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  523-7     Citation Subset:  IM    
Affiliation:
Otorhinolaryngology and Disturbances of Human Communication Department, Paulista Medical School, São Paulo Federal University, Brazil. lfmabreu@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Protein Electrophoresis
Disease Models, Animal
Humans
Microscopy, Electron, Scanning
Mouth Mucosa / cytology,  ultrastructure
Photomicrography
Protein-Energy Malnutrition*
Rats
Rats, Wistar
Tongue / cytology*,  ultrastructure
Weight Loss
Comments/Corrections
Comment In:
Braz J Otorhinolaryngol. 2012 Aug;78(4):7; author reply 8   [PMID:  22936128 ]

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