Document Detail

Histological study on intestinal diverticulum of tree shrew (Tupaia javanica).
MedLine Citation:
PMID:  12221937     Owner:  NLM     Status:  MEDLINE    
Tree shrews possess an intestinal diverticulum. We investigated this diverticulum with histological and immunohistochemical methods to determine whether this diverticulum was cecum or not. The ratio of the length of diverticulum/small intestine was apparently shorter than that of several primates. In the histological study, mucous membrane of the small intestine was shifted to that of the large intestine at the junction of the diverticulum. Histological features of the diverticulum were similar to those of the large intestine, but the shape of mucousal surface was rather simpler than that of the large intestine. Immunohistochemical study revealed 5-HT positive cells in the bottom of crypts and CD3- and CD 8-positive lymphocytes in lymphoid nodules. These findings suggest that the tree shrew has a cecum with primitive characteristics.
Masakazu Kakuni; Takashi Makita; Hery Wijayanto; Eiichi Hondo; Yasuo Kiso
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental animals / Japanese Association for Laboratory Animal Science     Volume:  51     ISSN:  1341-1357     ISO Abbreviation:  Exp. Anim.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-09-11     Completed Date:  2003-02-25     Revised Date:  2014-10-24    
Medline Journal Info:
Nlm Unique ID:  9604830     Medline TA:  Exp Anim     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  411-5     Citation Subset:  IM    
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MeSH Terms
Antigens, CD3 / analysis
CD8-Positive T-Lymphocytes / cytology
Cecum / anatomy & histology*
Intestine, Large / anatomy & histology
Intestine, Small / anatomy & histology
Mucous Membrane / cytology
Serotonin / analysis
Tupaiidae* / anatomy & histology*
Reg. No./Substance:
0/Antigens, CD3; 333DO1RDJY/Serotonin

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