Document Detail

Histological and microscopy FT-IR imaging study on the proliferative activity and angiogenesis in head and neck tumours.
MedLine Citation:
PMID:  14992397     Owner:  NLM     Status:  MEDLINE    
Micro Fourier transform infrared spectroscopy enables one to study small samples because of the high quality spectra that can be obtained. Biochemical and morphological changes between control and pathological tissues of head and neck tumours have been monitored drawing three-dimensional chemical maps of the main vibrational modes in the regions of interest. Comparison between spectral and histological data shows a satisfactory degree of accordance. Among all, proliferating and regressive states of the tumours can be identified.
P Bruni; C Conti; E Giorgini; M Pisani; C Rubini; G Tosi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Faraday discussions     Volume:  126     ISSN:  1359-6640     ISO Abbreviation:  Faraday Discuss.     Publication Date:  2004  
Date Detail:
Created Date:  2004-03-02     Completed Date:  2004-05-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9212301     Medline TA:  Faraday Discuss     Country:  England    
Other Details:
Languages:  eng     Pagination:  19-26; discussion 77-92     Citation Subset:  IM    
Dipartimento di Scienze dei Materiali e della Terra, Università Politecnica delle Marche, Ancona, Italy.
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MeSH Terms
Antigens, CD34 / biosynthesis
Carcinoma, Squamous Cell / pathology
Cell Division
Diagnostic Imaging
Gingival Neoplasms / pathology
Head and Neck Neoplasms / blood supply,  pathology*
Ki-67 Antigen / metabolism
Neovascularization, Pathologic / pathology*
Neprilysin / biosynthesis
Sarcoma / pathology
Spectroscopy, Fourier Transform Infrared
Reg. No./Substance:
0/Antigens, CD34; 0/Ki-67 Antigen; EC

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