Document Detail

Histological evaluation of the healing potential of the anterior cruciate ligament by means of augmented and non-augmented repair: an in vivo animal study.
MedLine Citation:
PMID:  18712354     Owner:  NLM     Status:  MEDLINE    
The purpose of this animal study was to investigate the healing potential of the anterior cruciate ligament following transaction at the femoral end, by means of both the augmented and the nonaugmented primary repair, focusing on the histological changes during a 12-month postoperative observation period with respect to necrosis and the loss of normal structures during the healing period. Twenty sheep were randomly assigned to nonaugmented primary ACL repair, or to augmented ACL repair using a polyethylene terephthalate (PET) band. At 2, 6, 16, 26 and 52 weeks postoperatively four sheep out of each group were sacrificed. Histological healing was achieved after 16 weeks for the augmented repair group and after 26 weeks for the nonaugmented repair group. The main difference between the two techniques was that the PET augmentation device protected the ligament from necrosis and ligamentization. In this group a consistently normal ligament was seen histologically during the entire postoperative observation period. The nonaugmented repaired ACLs underwent the processes of necrosis and ligamentization.
Helmut Seitz; Wolfgang A Menth-Chiari; Susanna Lang; Thomas Nau
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Publication Detail:
Type:  Journal Article     Date:  2008-08-19
Journal Detail:
Title:  Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA     Volume:  16     ISSN:  0942-2056     ISO Abbreviation:  Knee Surg Sports Traumatol Arthrosc     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-25     Completed Date:  2009-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314730     Medline TA:  Knee Surg Sports Traumatol Arthrosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1087-93     Citation Subset:  IM    
Department of Trauma Surgery, Judenburg-Knittelfeld General Hospital, Oberweggasse 18, 8750, Judenburg, Austria.
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MeSH Terms
Anterior Cruciate Ligament / injuries,  pathology*,  surgery*
Knee Joint / pathology*,  surgery*
Necrosis / prevention & control
Orthopedic Procedures / instrumentation,  methods*
Polyethylene Terephthalates
Recovery of Function
Suture Anchors*
Suture Techniques
Wound Healing*
Reg. No./Substance:
0/Polyethylene Terephthalates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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