Document Detail


Histological aspects of cervical ripening.
MedLine Citation:
PMID:  136067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is a close relationship between the rate of the uterine cervix opening during parturition and the presence or absence of a completely ripened cervix. In order to learn the basic pattern of the ripening of cervix, histological and histochemical studies were performed on the human uterine cervix during pregnancy. It was noted that the collagen bundles disintegrated into fine fibers and also underwent quantitative changes during the ripening process of the cervix. During pregnancy, the number of connective tissue cells was increased, but that of mast cells was decreased. Acid mucopolysaccharides in the cervical ground substance were found to increase in late pregnancy.
Histological aspects of cervical ripening were studied on the human uterine cervix during pregnancy. Cervical specimens were taken from 25 cases of cervical laceration of primiparous women immediately after delivery, 8 primiparous women whose cervixes opened 2-3 cm, and 5 cesarean-sectioned women with unripeness of cervix. The following histochemical techniques were used: alcian blue, azure A, hyaluronidase digestion, and chondroitinase ABC digestion. The collagen bundles disintegrated into fine fibers and also underwent quantitative changes during the ripening process of the cervix. The number of connective tissue cells was increased during pregnancy, but that of mast cells was decreased. In late pregnancy, acid mucopolysaccharides in the cervical ground substance were found to increase.
Authors:
M Ichijo; T Shimizu; Y Sasai
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  118     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  153-61     Citation Subset:  IM; J    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Alcian Blue / diagnostic use
Azure Stains / diagnostic use
Cervix Uteri / cytology*,  metabolism
Connective Tissue / metabolism
Connective Tissue Cells
Female
Glycosaminoglycans / metabolism
Humans
Labor, Obstetric*
Pregnancy
Chemical
Reg. No./Substance:
0/Azure Stains; 0/Glycosaminoglycans; 12040-44-7/Alcian Blue

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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