| Histological Findings of the Atrioventricular Conductive System in Street Heroin Addicts, Victims of Sudden Unexpected Death. | |
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MedLine Citation:
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PMID: 23083062 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A study of the atrioventricular (AV) conducting tissue was considered necessary for the examination of probable histologic changes that could justify the arrhythmias observed in street-heroin addicts. Postmortem coronary angiography and microscopic examination were performed in 50 heroin addicts (group A) and in 50 nonaddicts (group B), all male 16-40 years old. In group A, fatty and/or fibrous tissue replaced the AV node in 50% of cases while in group B in 14%. The main bundle was replaced by fatty and/or fibrous tissue in 44% in group A cases and 10% in group B. Intimal proliferation and fibromuscular dysplasia of the AV arteries in group A were correspondingly 26% and 14% and in group B 6% and 2%. Inflammation with focal and/or diffuse concentration of round cells of the AV node was detected in 54% in group A. These findings could explain a possible arrhythmia mechanism in this population. |
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Authors:
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Christos E Nerantzis; Constantinos M Couvaris; Socrates C Pastromas; Soultana K Marianou; Ilias D Boghiokas; Philippos N Koutsaftis |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-19 |
Journal Detail:
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Title: Journal of forensic sciences Volume: - ISSN: 1556-4029 ISO Abbreviation: J. Forensic Sci. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375370 Medline TA: J Forensic Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 American Academy of Forensic Sciences. |
Affiliation:
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Forensic Medical Service of Athens, Mikras Asias 75, GR-115 27, Athens, Greece. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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