| Histologic evaluation of a cornea in a patient with apolipoprotein A-I deficiency. | |
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MedLine Citation:
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PMID: 18362673 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report the histology of a cornea in a patient with apolipoprotein A-I (apoA-I) deficiency. METHODS: A cornea from a patient with apoA-I deficiency was obtained by keratoplasty and examined histologically. RESULTS: There were many small vesicles in the extracellular matrix throughout the corneal stroma. The vesicles were round or oval, and their diameters ranged from 200 nm to 2 microm. These histologic properties suggest that the small vesicles are lipid droplets. CONCLUSIONS: Myriad lipid droplets in the extracellular matrix in the corneal stroma induce diffuse corneal opacity in a patient with apoA-I deficiency. |
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Authors:
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Yasuhiro Osakabe; Shiro Amano; Shima Fukuoka; Satoru Yamagami |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cornea Volume: 27 ISSN: 0277-3740 ISO Abbreviation: Cornea Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-25 Completed Date: 2008-05-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8216186 Medline TA: Cornea Country: United States |
Other Details:
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Languages: eng Pagination: 372-3 Citation Subset: IM |
Affiliation:
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Department of Pathology, Tokyo Medical University, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Apolipoprotein A-I / deficiency*, genetics Cornea / ultrastructure* Corneal Opacity / etiology*, pathology*, surgery Female Frameshift Mutation Humans Keratoplasty, Penetrating |
| Chemical | |
Reg. No./Substance:
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0/Apolipoprotein A-I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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