Document Detail

Histologic and clinicopathologic features of Chinese patients with HBsAg-positive chronic active hepatitis.
MedLine Citation:
PMID:  3699809     Owner:  NLM     Status:  MEDLINE    
Needle biopsies of both the right and left lobes of the liver were performed during peritoneoscopy in 20 male patients with chronic active hepatitis B in Taiwan. Microscopic study of these biopsy specimens led to the recognition of three groups: 1) five patients in whom the lobular architecture was easily recognizable but in whom necrosis and early intralobular fibrosis were present, along with severe chronic inflammation of the portal tracts; 2) seven patients in whom the livers were characterized by early septal formation and a good regenerative response, but few recognizable lobules with normal architecture; and 3) eight patients in whom the disease had progressed to severe fibrosis with septal formation and tiny pseudolobules, indicative of early cirrhosis. The left lobe was the more severely damaged in 16 of the 20 patients.
S D Lee; H A Edmonson; M J Tong; C L Yeh
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  17     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-06-13     Completed Date:  1986-06-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  462-8     Citation Subset:  IM    
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MeSH Terms
China / ethnology
Chronic Disease
Hepatitis / complications,  immunology*,  pathology,  physiopathology
Hepatitis B Surface Antigens / analysis*
Liver / pathology
Liver Cirrhosis / etiology,  pathology
Liver Regeneration
Middle Aged
Reg. No./Substance:
0/Hepatitis B Surface Antigens

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